Abstract

Background/Aim: The positive effect of thermal mineral waters on human health has been known for a long time. Many pathophysiological mechanisms of action of balneotherapy are not specified. Patients with gonarthrosis often have elevated values of serum lipids. This study aimed to examine the effect of drinking sulphate-sulphide thermo mineral water on the lipid status of patients with gonarthrosis. Methods: A prospective clinical study followed 60 patients, both sexes, mean age 65.02 ± 1.03, with gonarthrosis. All inpatient underwent physical treatment with topical application of sulphate-sulphide mineral water. Patients of group A (N = 30) had the use of this mineral water as an additional therapy by drinking, unlike patients of group B (N = 30) who drank plain water. The level of serum lipids of these patients was monitored at admission and 4 weeks after. The variance analysis test (ANOVA) with a level of statistical significance p < 0.001 was used for statistical analysis. Results: A significant reduction in the levels of all lipid fractions in the serum of patients with gonarthrosis was found 4 weeks after the completion of inpatient physical treatment in both study groups. This decrease was statistically significant in patients of group A (p < 0.001). Conclusion: Drinking sulphate-sulphide mineral water in patients with gonarthrosis shows a positive effect on the reduction of serum lipid levels in the short-term follow-up period.

Highlights

  • Osteoarthritis (OA) is the most common joint disease and one of the main causes of pain and disability

  • This study aimed to examine the effect of internal application of sulphide-sulphate mineral water on the lipid status of patients with gonarthrosis

  • The total of 24 treatments included: transcutaneous electrical nerve stimulation (TENS) on the affected knee exercises to increase the range of motion in the knee and strengthen the quadriceps and hamstrings and locally applied baths of sulphate-sulphide mineral water temperature 31-33 ° C for 20 minutes

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Summary

Introduction

Osteoarthritis (OA) is the most common joint disease and one of the main causes of pain and disability. The increase in bile acid excretion is related to the alkaline nature of mineral waters and the osmotic effect. Lipid-reducing effects of sulphate-sulphide mineral water in patients with knee osteoarthritis.

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