Abstract
Background: Obesity is a common metabolic disease world-wide and dyslipidemias among the most common metabolic disorders associated with obesity. The present study was undertaken to assess lipid profile level among healthy subjects and their relation with obesity.Subjects and Methods: This cross sectional study was conducted on 100 subjects. General information related to data such as name, age, gender etc. was recorded in case history proforma. BMI was evaluated based on formula of BMI = Weight (kg)/Height (m)2. Based on BMI, subjects were divided into two groups according to their BMI values as- group I- Obese and Group II- Non obese. Group I had 65 and group II had 35 subjects. Lipid profile was done.Results: There was significant difference in group I and group II regarding waist circumference (WC), BMI (kg/m2), body adiposity index (BAI), visceral adiposity index (VAI), total cholesterol (TC) (P< 0.05). Waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), HDL- C, LDL- C, TG, TC/HDL- C, LDL-C/HDL-C and TG/HDL-C was non- significant (P< 0.05). There was negative correlations between BMI and TC, LDL-C, HDL-C; WC, WHR, VAI and HDL-C and positive significant correlations were found between WC, WHR, and TG/HDL-C, as well as between VAI andTC, TG, TC/HDL-C, LDL/HDL-C, and TG/ HDL-C.Conclusion:Authors found that there was alteration of lipid profile in obese subjects. VAI is strongly related with lipid profile and may be considered as reliable obesity index in obese patients with dyslipidemias.
Highlights
Human body requires lipids such as cholesterol, triglycerides and fatty acids
Obesity is often described by classical parameters such as body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR)
Results of the some recently published studies suggest that waist-to-height ratio (WHtR), the newer obesity index, may be helpful for assessing risk of metabolic complications, including dyslipidemia, and it may be a predictor of cardiovascular events in obese patients
Summary
Human body requires lipids such as cholesterol, triglycerides and fatty acids. In condition of dyslipidemia there is derangement of plasma lipids and their normal levels. [1] It has been observed that dyslipidemia is considered to be the cause of atherosclerosis resulting in conditions like leading to cerebrovascular disease (CVD), coronary heart disease and peripheral vascular disease. [2] The process of atherosclerosis starts in childhood and risk parameters such as dyslipidemia, positive family history, obesity, high blood pressure and diet play an important role in progression of CVD. Assessment of body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) helps in diagnosis of obesity. Obesity is often described by classical parameters such as body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR). Results of meta-regression analysis of prospective, randomized studies showed that WHR and WC may play important roles in assessment of increased risk of cardiovascular (CV) events. Radhika & Thomas: Lipid Profile Level among Healthy Subjects and Their Relation with Obesity icant correlation between anthropometric variables and lipid parameters. [6] Considering this, the present study was undertaken to assess lipid profile level among healthy subjects and their relation with obesity Radhika & Thomas: Lipid Profile Level among Healthy Subjects and Their Relation with Obesity icant correlation between anthropometric variables and lipid parameters. [6] Considering this, the present study was undertaken to assess lipid profile level among healthy subjects and their relation with obesity
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