Abstract
The acylation of several pyranoses and fructose with fatty acids by lipases in a solid-phase system was investigated. Highest selectivity was found using lipase from Candida antarctica B immobilized on polypropylene EP 100. For β-D(+)-glucose 98% mono- and 2% diacylation using palmitic acid in t-butanol were observed. Much lower selectivities were achieved with D-(+)-mannose (75% monoacylation) and D(+)-galactose (50% monoacylation), which was explained by the different orientation of the C2-hydroxyl groups. The selectivity in the acylation of fructose was significantly influenced by the fatty acid chain length and the organic solvent. Monoacylation was favored in less hydrophobic solvents (e.g. t-butanol) using long chain fatty acids.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
