Abstract
The rates of linoleic acid solubilization in aqueous solutions of sodium taurodeoxycholate were measured at 37°C using a spinning liquid disc. The liquid disc is made of a polymer film whose pores contain the liquid being solubilized. Measurements of heptanoic acid dissolution show that the liquid disc behaves like a solid disc of 10% smaller area. Measurements of linoleic acid solubilization show characteristics of diffusion and surface reaction in series. The surface reaction is apparently controlled by bile salt adsorption.
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