Abstract
Bacteriophage Mu particles were disrupted by treatment at high pH, and the DNA released from the phage was analyzed by electron microscopy. The DNA appeared to be associated with the proximal end of the tail. Denaturation maps of Mu DNA were obtained by heating and ultraviolet irradiation. The profiles of the two maps were comparable and indicated that the same end of the Mu genome was always connected to the sheath structure. Analysis of the DNA fragments after treatment of the DNA-tail complex with the endonuclease Eco R1 showed that the variable end of the Mu DNA was attached to the tail.
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