Abstract
Introduction and hypothesisThe Global Prevalence Study of Infections in Urinary tract in Community Setting (GPIU.COM) includes epidemiological aspects of acute cystitis (AC) in women in Germany and Switzerland. The primary study relates to the German version of the Acute Cystitis Symptom Score (ACSS), a self-reporting questionnaire for self-diagnosis and monitoring the symptomatic course of AC in women. The current study aimed to analyze the validity and reliability of the German ACSS in German-speaking female patients with AC in Switzerland.MethodsAnonymized patient data were collected and analyzed from women with AC at the first visit (diagnosis) and follow-up visits as baseline and controls, respectively. Data from 97 patients with a median age of 41 years underwent analysis. Psychometric and diagnostic characteristics of the ACSS were measured and statistically analyzed.ResultsAverage internal consistency of the ACSS resulted in a Cronbach’s alpha (95% CI) of 0.86 (0.83; 0.89) and did not differ significantly between the Swiss and German cohorts. Diagnostic values of the ACSS for the Swiss cohort were relatively lower than for the German cohort, possible due to discrepancies between definitions of UTI in national guidelines.ConclusionsThe analysis showed that the German version of the ACSS is also suitable for use in the German-speaking female population of Switzerland. Minor differences in definitions of AC between German and Swiss guidelines explain the observed discrepancies in diagnostic values of the ACSS between cohorts.
Highlights
Introduction and hypothesis The Global PrevalenceStudy of Infections in Urinary tract in Community Setting (GPIU.COM) includes epidemiological aspects of acute cystitis (AC) in women in Germany and Switzerland
Uncomplicated urinary tract infections are common in the global female population, accounting for at least one symptomatic episode of acute cystitis during a lifetime, and about one-third of women first experience an acute episode before the age of 24 [1, 2]
This study was initiated by the European Section for Infections in Urology (ESIU), which is affiliated with the European Association of Urology (EAU), and aimed to highlight contemporary aspects of uncomplicated urinary tract infections (uUTI) in women, such as the prevalence of AC and its relevant risk factors, the most common causative uropathogens and their resistance to commonly prescribed antimicrobial agents, etc
Summary
Introduction and hypothesis The Global PrevalenceStudy of Infections in Urinary tract in Community Setting (GPIU.COM) includes epidemiological aspects of acute cystitis (AC) in women in Germany and Switzerland. This study was initiated by the European Section for Infections in Urology (ESIU), which is affiliated with the European Association of Urology (EAU), and aimed to highlight contemporary aspects of uUTI in women, such as the prevalence of AC and its relevant risk factors, the most common causative uropathogens and their resistance to commonly prescribed antimicrobial agents, etc. This part of the GPIU.COM-Study aimed to test the strategy of unified standards and tools for possible “pros and cons” in a German-
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