LINFOIDE HYPERPLASIA IN MOUTH: CASE REPORT

Abstract

A 49-year-old female patient, a farmer, presented as the main complaint the presence of "lumps in the mouth that hurt when touching." At the clinical examination, a nodule of approximately 1.5 cm, dark red color, smooth surface, flaccid consistency, and painful symptoms were observed in the left tonsillar pillar. The other nodules were diagnosed as valvular papillae. An excisional biopsy was performed and the material was sent to the Oral and Maxillofacial Pathology laboratory for analysis. Histopathological examination revealed a proliferation of lymphoid cells in a follicular arrangement. In the focal area, diffuse arrangement of lymphocytes with a monotonous appearance was observed, irregular nuclei, sometimes with condensed chromatin, and scarce cytoplasm. The diagnosis was lymphoid cell lesions. Immunohistochemical reactions were performed, which were positive for the anti-CD3 and CD20 antibodies. After the immunohistochemical analysis, the diagnosis of lymphoid hyperplasia is concluded. Patient is in disease-free follow-up after 2 years. A 49-year-old female patient, a farmer, presented as the main complaint the presence of "lumps in the mouth that hurt when touching." At the clinical examination, a nodule of approximately 1.5 cm, dark red color, smooth surface, flaccid consistency, and painful symptoms were observed in the left tonsillar pillar. The other nodules were diagnosed as valvular papillae. An excisional biopsy was performed and the material was sent to the Oral and Maxillofacial Pathology laboratory for analysis. Histopathological examination revealed a proliferation of lymphoid cells in a follicular arrangement. In the focal area, diffuse arrangement of lymphocytes with a monotonous appearance was observed, irregular nuclei, sometimes with condensed chromatin, and scarce cytoplasm. The diagnosis was lymphoid cell lesions. Immunohistochemical reactions were performed, which were positive for the anti-CD3 and CD20 antibodies. After the immunohistochemical analysis, the diagnosis of lymphoid hyperplasia is concluded. Patient is in disease-free follow-up after 2 years.