Linear sweep voltammetry of 9-β- d-ribofuranosyluric acid 5′-monophosphate in aqueous and micellar media

Abstract

Linear sweep voltammetric behaviour of 9-β- d-ribofuranosyluric acid 5′-monophosphate (UA-9R-5′-P) has been studied in phosphate buffers of pH 3.0 and 7.0 at the pyrolytic graphite electrode in aqueous and micellar media. At pH 3.0 in the presence of non-ionic and anionic surfactants, UA-9R-5′-P exhibited a single well-defined 2e, 2H + oxidation peak, whereas in the presence of cationic surfactant (CTAB) the oxidation peak I a showed a tendency to split into two peaks indicating that the 2e, 2H + oxidation of UA-9R-5′-P in peak I a reaction occurs in two 1e steps. The effect of cationic surfactant at pH 3.0 is explained on the basis of hydrophobic penetration of cationic species in cationic micelles. The products of electrode reaction in micellar medium were found as alloxan, urea and ribosyl phosphate at pH 3.0 and ribose, allantoin and 5-hydroxyhydantoin 5-carboxamide at pH 7.0 and were similar to those observed in aqueous media.