Linear regression analysis on the relationship between breast cancer patients′ mindfulness level and hormonal therapy compliance and their quality of life

Abstract

Objective To investigate the relationship between breast cancer patients′mindfulness level and endocrine treatment compliance and quality of life, so as to provide the references for improving the compliance of breast cancer patients. Methods A total of 168 breast cancer patients who received a through treatment of supplementary endocrine drugs for the first time were investigated by the mindful attention awareness scale(MAAS) in Chinese version, the hormonal therapy compliance scale and quality of life scale, and the relationship between breast cancer patients′mindfulness level and endocrine treatment compliance were analyzed. Results The total scores of mindfulness level, compliance and quality of life were respectively(78.2±8.4), (12.1±4.3) and(42.6±9.8). The scores of compliance and quality of life of patients of group with high mindfulness level were significantly lower than that of group with low mindfulness level group(P<0.05). Pearson results showed that the scores of mindfulness level had a negative correlation with the scores of hormonal therapy compliance and quality of life respectively(P<0.01). Logistic linear regression analysis showed that the three dimensions of mindfulness including observation, description and perception actions can predict 55.6% of the variance of the compliance behavior and 53.1% of the variance of quality of life. Conclusions The level of mindfulness awareness can effectively predict hormonal therapy and quality of life of patients with breast cancer.Measures should be taken to improve the patients' mindfulness awareness, so as to improve their compliance of endocrine treatment and quality of life. Key words: Breast cancer; Mindfulness; Compliance; Quality of life