Abstract

In this communication we illustrate the use of some recent results on the application of linear rank procedures to censored matched data. We re-analyze the time-to-tumor littermatched data of Mantel, Bohidar and Ciminera (1977), discussing our choice of procedure and comparing our approach with the analysis of the same data by Mantel and Ciminera (1979). We also demonstrate the use of a convenient algorithm for computing efficient scores on censored data. The data of Mantel et al. (1977), which we shall refer to as the 'rat-litter data,' are timeto-tumor, arbitrarily right-censored, litter-matched data for 50 rat litters. For each litter there are observations on three female litter mates: one received a treatment and the other two served as controls. The goal of this analysis is to determine whether the treatment has had an effect on the uncensored distributions of the time to tumor.

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