Abstract

The moment analysis approach, which is widely used in single-component isothermal chromatography, is applied to study two-component perturbation chromatography with linear nonequilibrium adsorption. The interference between components is included through the equilibrium isotherms. Using moment analysis and matrix diagonalization, expressions for the first and second chromatographic moments of components and waves, written in matrix form, are derived. The well-known results for moment solution of the single-component case are extended to the two-component case. The results clearly show the interference between components and give a good understanding of multicomponent adsorption and interference. The approach can easily be extended to more general cases.

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