Linear nevus sebaceous syndrome with lissencephaly

Abstract

Linear nevus sebaceous syndrome is a congenital neurocutaneous syndrome comprising of nevus sebaceous, seizures and mental retardation. We report a 6 month old female child with a linear nevus sebaceous over the face and scalp, whose brain imaging revealed ipsilateral lissencephaly with hemimegalencephaly. Lissencephaly is rarely reported in this syndrome.