Abstract
The preliminary work was presented at the meeting of the Expert Panel on Biopharmaceutics Drug Classification System of the Food and Drug Administration on October 21, 1997 at Food and Drug Administration in Rockville, Maryland. The content of this paper was also presented under the title, Drug absorption studies in vivo in rats for predicting fraction of drug absorbed in humans at the AAPS Workshop on Permeability Definitions and Regulatory Standards for Bioequivalance, August 17-19, 1998, Arlington. Virginia.
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