Abstract
Tracing the fate of individual cells and their progeny is necessary and significant for stem cell research and cancer research. Changes in lineage-specific transcription factor levels during lineage commitment are gradual and continuous. Development of single-cell sequencing technology allows many different states of cells to be sequenced at an unprecedented resolution, and it has been proved that single-cell transcriptomics meets lineage tracing. Here, we introduce a detailed protocol for the lineage tracing by single-cell transcriptomics to clarify the dynamics of lineage commitment.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
