Abstract
LINE-1 DNA methylation as a biomarker of early carcinogenesis
Highlights
Another consideration of molecular epidemiology research involves the investigation of genetic factors that affect the molecular processes under study
By incorporating genetic factors into the study of molecular epidemiology, it becomes possible to target those individuals that are at an increased risk of disease due to genetic polymorphisms
Long interspersed nuclear element-1 (LINE-1) DNA methylation is a specific form of DNA methylation, and an established precursor to carcinogenesis
Summary
Another consideration of molecular epidemiology research involves the investigation of genetic factors that affect the molecular processes under study. By incorporating genetic factors into the study of molecular epidemiology, it becomes possible to target those individuals that are at an increased risk of disease due to genetic polymorphisms. When data on lifestyle exposures and genetic factors are combined, a more complete picture of the risk of chronic diseases begins to form.
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