Limits of Normal Indicators of the Amount of Formal Elements in the Blood of 3-month-old Rabbits

Abstract

In our scientific research, several physiologically and biochemically important parameters were studied in the blood of 3-month-old rabbits: glucose hemostasis, pH-indicator and the amount of immune hemoglobin. In this experiment, we obtained interesting facts about hypoxia and physical loads, the initial changes in blood and their dynamics during the joint application of these factors. We considered that in the experimental work carried out in this direction, it is also important to study the quantitative changes of the main morphological (cellular) structures-shaped elements in the blood of 3-month-old rabbits in the above-mentioned experimental models. From the obtained results, it became clear that the physiological necessity of neither leukocytes, nor lymphocytes, nor monocytes to strengthen the body’s immune defense system during such physical loads is almost too weak, this was confirmed in a number of experiments. This is also shown by our research work. However, a number of experimental evidence show that very high motor activity can lead to a more or less increase in the number of platelets in the animal body. Due to the increase of erythrocytes and platelets, hematological parameters such as hematocrit and thrombocrit can also increase. In the latter version of this study, we induced 3-month-old rabbits to perform a 10-min act of treadmill running immediately after 20 min of severe hypoxic exposure. It is very interesting that in the first hours of the experiment, the shape elements of the blood and other morphometric indicators (hemotocrit and thrombocrit levels) were manifested in 3-month-old rabbits only within the limits of changes that occurred when severe hypoxia was applied. Therefore, it can be concluded that hypoxia is the factor affecting blood and its composition in a complex experimental model such as hypoxia + physical load.