Abstract

Limited view tomographic reconstruction aims to reconstruct a tomographic image from a limited number of projection views arising from sparse view or limited angle acquisitions that reduce radiation dose or shorten scanning time. However, such a reconstruction suffers from severe artifacts due to the incompleteness of sinogram. To derive quality reconstruction, previous methods use UNet-like neural architecturesto directly predict the full view reconstruction from limited view data; but these methods leave the deep network architecture issue largely intact and cannot guarantee the consistency between the sinogram of the reconstructedimage and the acquiredsinogram, leading to a non-ideal reconstruction. In this work, we propose a cascaded residual dense spatial-channel attention network consisting of residual dense spatial-channel attention networks and projection data fidelity layers. We evaluate our methods on two datasets. Our experimental results on AAPM Low Dose CT Grand Challenge datasets demonstrate that our algorithm achieves a consistent and substantial improvement over the existing neural network methods on both limited angle reconstruction and sparse view reconstruction. In addition, our experimental results on Deep Lesion datasets demonstrate that our method is able to generate high-quality reconstruction for 8 major lesion types.

Highlights

  • T OMOGRAPHY imaging is a non-invasive projectionbased imaging technique that visualizes an object’s internal structures and finds wide applications in healthcare, security, and industrial settings [1]–[3]

  • Inspired by the recent advances in image super-resolution network designs and the projection data constraint in model-based iterative reconstruction (MBIR), we designed a customized Residual Dense Spatial-Channel Attention Network (RedSCAN) as our backbone image reconstruction network, and we built a projection data fidelity layer that can be embedded in deep networks

  • We demonstrate the feasibility of our CasRedSCAN on both limited angle (LA) and sparse view (SV) tomographic reconstruction tasks, as shown in the result section

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Summary

Introduction

T OMOGRAPHY imaging is a non-invasive projectionbased imaging technique that visualizes an object’s internal structures and finds wide applications in healthcare, security, and industrial settings [1]–[3]. Tomography imaging techniques such as medical Computed Tomography (CT) based on x-ray projections, Positron Emission Tomography (PET), and Single-photon Emission Computed Tomography (SPECT) based on gamma-ray projections are indispensable imaging modalities for disease diagnosis and. B. Zhou is with the Department of Biomedical Engineering, Yale University, New Haven, CT, 06511, USA. Liu are with the Department of Biomedical Engineering and the Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, 06511, USA

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