LIMITED TREATMENT OPTIONS FOR PRIMARY HYPEROXALURIA WITH RENAL INSUFFICIENCY

Abstract

Primary hyperoxaluria (PH) is a rare autosomal recessive metabolic disorder in which the serum levels of oxalate increase because of overproduction.The renal tubule is the primary target of the oxalate deposit, which damages the kidney and leads to cause ESRD. Here, we present a 54-year-old man with a terminal kidney disease; which is dependent on hemodialysis and is likely due to type 2 or 3 PH. Renal insufciency is uncommon to be found in PH patients. With exceedingly high levels of serum oxalate (70 ฀mol/L), this patient had few treatment options available for his rare condition.This report details a unique introduction to a rare condition where renal biopsy was instrumental to reach the diagnosis.