Abstract
Publisher Summary This chapter discusses a study that is intended to determine whether abnormal electroencephalogram (EEG) findings obtained by quantitative EEG (qEEG) frequency analysis are necessarily related to the pathology of brain lesions. Quantitative EEG frequency analyses are made under experimental conditions of acute focal ischemia and experimentally induced brain tumors in various animals. In order to characterize significant features of the pathological EEG, other parameters such as blood flow, electrolyte homeostasis, and water content of the brain are also measured in the same animals. A specific relationship between EEG alterations and such parameters, prove to be applicable to the pathognomonic differentiation of the human cerebral brain lesions. The chapter describes EEG using qEEG analysis in patients suffering from cerebrovascular disease, brain tumors, intracerebral hemorrhage, and head trauma. Quantitative EEG frequency analysis determines the alterations of total EEG intensity, of the activity in conventional slow and fast wave bands and of the ratios of delta plus theta to alpha plus beta intensity (frequency index), which are related to changes of cerebral blood flow, electrolyte homeostasis and water content in experimental brain ischemia and brain tumors.
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