Limitations of Alzheimer’s Disease Medications

Abstract

Alzheimer’s disease is an irreversible, progressive brain disorder affecting more than 6.5 million Americans that slowly destroys memory and thinking skills and, eventually, the ability to carry out simple tasks. While the specific causes of Alzheimer’s are not fully known, it is characterized by changes in the brain-including amyloid beta plaques and neurofibrillary, or tau tangles that result in the loss of neurons and their connections. These changes affect a person’s ability to remember and think. Individual responses to Alzheimer’s medications can vary. Some people may experience significant cognitive benefits, while others may have a more modest response or no response at all. The cognitive benefits provided by some medications are generally temporary. The medication may slow down the rate of cognitive decline, but it does not stop the progression of Alzheimer's disease. Some medications are more effective in the early and moderate stages of Alzheimer's disease. This article in brief described the limitations of the drugs that are used in the treatment of Alzheimer’s disease.