Abstract
Limbic encephalitis (LE) is a clinical entity related to a mesial temporal lesion resulting in a combination of anterograde memory dysfunction, behavioral changes, and seizures. The most common causes of limbic encephalitis are Herpes Simplex Virus (HSV) encephalitis, autoimmune encephalitis. Neurosyphilis is an exceptional aetiology. The early diagnosis and management of the disease determine the prognosis. This clinical course highlights the diagnostic challenge limbic encephalitis can cause and the importance of considering neurosyphilis in patients with specific or unspecific neurological symptoms. We report a case of a mesiotemporal form of neurosyphilis revealed by a LE.
Highlights
Limbic encephalitis (LE) is a clinical entity related to a mesial temporal lesion resulting in a combination of anterograde memory dysfunction, behavioral changes, and seizures
We report a case of a mesiotemporal form of neurosyphilis revealed by a LE
Cerebral MRI may be normal at an early stage, but the pathognomonic lesions are localized at the limbic region and appear as a hypersignal on T2 and fluid-attenuated inversion recovery (FLAIR) without contrast enhancement
Summary
Limbic encephalitis is a clinical entity related to a mesial temporal lesion resulting in a combination of anterograde memory dysfunction, behavioral changes, and seizures. Cerebral MRI may be normal at an early stage, but the pathognomonic lesions are localized at the limbic region and appear as a hypersignal on T2 and fluid-attenuated inversion recovery (FLAIR) without contrast enhancement. The etiologies of LE are diverse: paraneoplastic, autoimmune, Hashimoto encephalitis, and infectious diseases especially herpetic; syphilis is a very rare cause
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
