Abstract
BackgroundWe tried to compare the functional and psychosocial outcomes after various reconstruction methods according to tumor location following resection of osteosarcoma in distal femur.MethodsWe retrospectively reviewed 51 patients who underwent limb-salvage surgery of osteosarcoma in distal femur in our institution, 30 males and 21 females with an average age of 21 years (range 13–51 years). We classified osteosarcoma in distal femur into 3 types, and organized affected limb reconstruction methods after wide resection. MSTS and QOL scores were used to analyze the functional and psychological outcomes.ResultsAfter a mean follow-up of 43 months (12–225 months), there is no difference on functional results and QOL scores among three reconstruction groups (p > 0.05) and among three types groups (p > 0.05). No difference could be noticed on tumor-free survival and total survival among three reconstruction groups (p > 0.05) and three type groups (p > 0.05). In ≤2-year, better functional scores could be found in prosthesis group, rather than the other two inactivated-bone groups (p < 0.05).ConclusionsBiological reconstruction with alcohol-inactivated autograft replantation could avoid prosthesis related complications and achieved comparable results with prosthesis following resection of osteosarcoma in distal femur. Different reconstruction options could be chosen according to tumor location, such as the distance to Insall line.Electronic supplementary materialThe online version of this article (doi:10.1186/1471-2474-15-453) contains supplementary material, which is available to authorized users.
Highlights
We tried to compare the functional and psychosocial outcomes after various reconstruction methods according to tumor location following resection of osteosarcoma in distal femur
The other purpose was to determine whether the reconstruction option of alcohol-inactivated autograft replantation could be comparable with prosthesis following resection of osteosarcoma in distal femur
When the affected limb is reconstructed after the resection of a malignant tumor in adolescence, such reconstruction is associated with a variety of problems, including an expectation of joint function due to postoperative articulation preservation, measures to be taken to cope with high levels of physical activity, and problems related to social adaptation
Summary
We tried to compare the functional and psychosocial outcomes after various reconstruction methods according to tumor location following resection of osteosarcoma in distal femur. Due to the various anatomical factors unique to juxtaarticular osteosarcomas around the knee, the reconstruction in distal femur remains a challenging problem. We classified osteosarcoma in distal femur encountered at our department into 3 types according to the location of the tumor by preoperative MRI, and organized affected limb reconstruction methods after wide resection. We performed this study to compare the functional and psychosocial outcomes of limb-salvage surgery after various reconstruction methods according to tumor location following resection of osteosarcoma in distal femur. The other purpose was to determine whether the reconstruction option of alcohol-inactivated autograft replantation could be comparable with prosthesis following resection of osteosarcoma in distal femur
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