Abstract

Limb-body wall complex (LBWC) is a rare, congenital defect defined by lateral body-wall defects, limb reduction abnormalities and/or craniofacial defects. The developmental pathogenesis as well as the etiology of LBW complex is controversial and has no sex or familial predilection. The poor prognosis of LBWC necessitates an early antenatal diagnosis. Serum alpha-fetoprotein measurement and ultrasonographic examination is the key to prenatal diagnosis. Prenatally, the abnormal fetoplacental attachment can be detected ultrasonographically by the end of the first gestational trimester. Postnatal, the examination of placenta, umbilical cord and membranes is crucial in confirming the diagnosis of LBWC. The present case is associated with amniotic adhesive bands, thoraco-abdominoschisis, minor encephalocele, and belongs to the category of LBWC with craniofacial defects.

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