Abstract
The incorporation of DL-[β-14C]phenylalanine into podophyllotoxin (1) has been demonstrated. The subsequent stepwise degradation to 3′,4′-methylenedioxy-3,4,5-trimethoxybenzophenone bearing a 14C-carbonyl label establishes the in vivo synthesis of the carbon skeleton of this lignan.
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More From: Journal of the Chemical Society, Perkin Transactions 1
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