Lignan, phenylpropanoid and iridoid glycosides from Pedicularis torta

Abstract

Six new lignan glucosides, tortosides A-F were isolated from whole plants of Pedicularis torta, along with 11 known compounds, (+)dihydrodehydrodiconiferyl alcohol-4-O-α- l-rhamnopyranoside , (+)-dihydrodehydrodiconiferyl alcohol-4-O-β- d-glucopyranoside , (+)-dihydrodehydrodiconiferyl alcohol-9-O-β- d-glucopyranoside , (+)-dehydrodiconiferyl alcohol-4-O-β- d-glucopyranoside , cistanosides C and D, verbascoside, 8-epiloganin, gardoside methyl ester, shanzhiside methyl ester and loganic acid. On the basis of spectral and chemical evidence, tortosides A-F were determined to be epi-syringaresinol-4″-O-β- d-glucopyranoside , 5,5′- dimethoxylariciresinol-4′-O-β- d-glucopyranoside , 5′,5″- demethylsyringaresinol-4″-O-β- d-glucopyranoside , (+)-dehydrodiconiferyl alcohol-9-O-β- d -4″-O- methylglucopyranoside , (+)-5-methoxydihydrodehydrodiconiferyl alcohol-9′-O-β- d-glucopyranoside and (+)-dehydroconiferyl alcohol-8,5′-dehydroconiferyl aldehyde-9-O-β- d-glucopyranoside , respectively.