Abstract

First, I would like to congratulate Sangmin Park and collaborators on their excellent article entitled “Lighthouse in the open sea of spastic ataxia.” The authors report the case of a 32-year-old patient with spastic ataxia and low arylsulfatase A (ARSA) activity range who was initially diagnosed as having metachromatic leukodystrophy (MLD). Their diagnosis was subsequently reevaluated based on genetic testing and particularly brain MRI imaging findings and they reached a definite diagnosis of spastic paraplegia type 11 (SPG11).

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