Abstract

To investigate the potential usefulness of artificial bright light in nonseasonal depression, investigators in Canada randomized 122 medication-free patients with moderately severe, nonpsychotic, nonbipolar major depression to one of four 8-week, double-blind treatments: fluoxetine (20 mg) + 30 minutes of bright light (10,000 lux) in the mornings, pill placebo + bright light, fluoxetine + light placebo (inactive negative-ion generator), or double placebo …

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