Abstract
目的 探讨血清游离轻链正常的λ轻链型多发性骨髓瘤的实验室特征与临床意义。 方法 报道1例血清游离轻链水平及比值正常的λ轻链型多发性骨髓瘤,采用免疫比浊法、免疫固定电泳等对患者血清及尿液进行综合分析,并复习相关文献。 结果 患者正常免疫球蛋白水平下降,骨髓中出现大量异型浆细胞。免疫固定电泳:微量λ型,血清蛋白电泳无M带,本周蛋白阴性。血清游离轻链水平及比值正常。诊断为λ轻链型多发性骨髓瘤。 结论 血清游离轻链正常的轻链型多发性骨髓瘤实验室表现与非分泌型多发性骨髓瘤虽有相似之处,但有区别,免疫固定电泳有助于两种疾病的鉴别。
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