Light and electron microscopic studies of Escherichia coli-coliphage interactions II. The electron microscopic cytology of the E. coli B-T2 system

Abstract

High contrast electron microscopic observations were made at known intervals after infection of E. coli B cells infected with T2 phage. During the first half of the latent period, marginal vesicular areas replaced the alternating dark and light patterning of normal cells. The latter half of the latent period was characterized by gross changes in the texture of the cytoplasm and by the gradual internal build-up first of phage “Anlagen” and second of mature phage progeny.