Ligand electronic effects in the palladium catalyzed asymmetric allylic alkylation reaction with planar chiral diphosphine-oxazoline ferrocenyl ligands

Abstract

A series of planar chiral diphosphine-oxazoline ferrocenyl ligands with different electronic properties were successfully used in the asymmetric allylic substitutent reaction. The enantioselectivity of this reaction was affected by the electronic nature of the ligands. When the electronic effect was coincident with the steric effect of ligand, a higher ee value was observed.