Abstract

Biodegradable material such as poly(lactic acid) (PLA) can be generated with great control of polymer molecular weight and dispersity using a large range of metal-based catalysts. PLA is generated from the ring-opening polymerization of cyclic ester lactide, either biologically derived L-lactide or racemic lactide, using a variety of catalysts. A central challenge in this field is controlling the mechanical properties of PLA by controlling the tacticity of polymers generated from racemic lactide. This chapter describes various efforts to control PLA tacticity through targeted ligand design of tri- and tetradentate ligand frameworks.

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