Lifestyle Risk Factors for Metabolic Syndrome in Patients with Rheumatoid Arthritis

Abstract

The aim was to measure the prevalence of metabolic syndrome and the associated risk factors in patients with rheumatoid arthritis.This study was conducted on a sample size of 142 patients enrolled conveniently. The Metabolic syndrome was defined according to NCEP ATP III (National Cholesterol Education Program Adult Treatment Panel III) criteria. The multivariable logistic regression model was built using a backward elimination process to assess the relationship between metabolic syndrome and independent variables.Adjustment of the model was done for age, sex, diet, mood, sleep, physical activity, social activity, smoking, disease characteristics, and medications.The mean (SD) age of patients was 52 (13) years, and 82% were women. Most patients received combination therapy with prednisolone, hydroxychloroquine and methotrexate.There was a significant association between metabolic syndrome and the following factors in the multivariable final model. Using leflunomide medications and poor sleep quality were associated with higher odds of metabolic syndrome in patients with rheumatoid arthritis. Patients who were prescribed sulfasalazine had lower odds of metabolic syndrome.