Abstract
Background:Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age. PCOS has a significant negative impact on the health-related quality of life (HRQoL) and psychological function of women, of which there are reports of high levels of depression in women with PCOS compared to those without PCOS. However, the evidence surrounding the effects of exercise and/or dietary intervention participation on the HRQoL of women with PCOS is limited. Therefore, our objective is to examine the effects of lifestyle interventions (definition include exercise-only, diet-only, exercise + diet and behavioral or combined) on health-related quality of life or general quality of life in women with PCOS.Methods:We will conduct an update of systematic review and we will follow the recommendations and guidelines of the Cochrane handbook for systematic reviews and Preferred Reporting Items for Systematic Review and Meta-Analysis Protocol (PRISMA-P). We will search the studies in the following databases: MEDLINE. PubMed, PsychINFO, Embase, SportDiscus, Web of Science, Cochrane Database (via Cochrane library), Cochrane Controlled Register of Trials (CENTRAL), and Google Scholar (advance). Manual search of the reference list of identified works, without language and year restrictions. The process of study selection and data extraction will be performed independently by 2 reviewers, with a third reviewer being responsible for the final decision in case of disagreement between the first two. We will use Egger funnel chart to evaluate possible publication biases, in addition, when possible we will perform a subgroup/meta-regression analysis. The strength of the evidence will be assessed according to the Grading of Recommendations Assessment, Development, and Evaluation (GRADE).Protocol registry:PROSPERO number: CRD42019124176.
Highlights
Polycystic ovary syndrome (PCOS) is a common endocrine dysfunction among women of reproductive age, with a prevalence of 4% to 12% but its etiology remains unknown.[1]
Previous systematic reviews have shown the existence of consistent data on the effects of exercise on health-related quality of life (HRQoL) in the adult population with certain types of disease.[27,28,29]
Few studies in the literature evaluate the effect of physical exercise or interventions for lifestyle changes on the quality of life of women with PCOS.[30,31]
Summary
Polycystic ovary syndrome (PCOS) is a common endocrine dysfunction among women of reproductive age, with a prevalence of 4% to 12% but its etiology remains unknown.[1] The symptoms of PCOS such as hirsutism, menstrual irregularity and infertility cause associated morbidities that generate negative consequences in the psychological and interpersonal functioning of individuals.[2]. Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age. PCOS has a significant negative impact on the health-related quality of life (HRQoL) and psychological function of women, of which there are reports of high levels of depression in women with PCOS compared to those without PCOS. Our objective is to examine the effects of lifestyle interventions (definition include exercise-only, diet-only, exercise + diet and behavioral or combined) on health-related quality of life or general quality of life in women with PCOS
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