Abstract
Dual antiplatelet therapy with aspirin and P2Y12 platelet receptor inhibitor is a cornerstone of treatment in acute coronary syndrome (ACS) [1]. Ticagrelor is a novel, potent, direct P2Y12 antagonist with rapid onset of action and intense, consistent platelet reactivity inhibition. In patients with ACS ticagrelor was superior to clopidogrel in decreasing major adverse cardiac events [2]. Therefore, ticagrelor (together with another P2Y12 inhibitor prasugrel) is preferred over clopidogrel [1], and is widely used in the setting of ACS.
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