Abstract
Objective To evaluate the change in intrauterine pressure during thermal balloon endometrial ablation and to identify risk factors associated with treatment failure. Design Prospective observational study. Setting University-affiliated teaching hospital. Patient(s) Seventy two consecutive patients with idiopathic menorrhagia refractory to medical treatment. Intervention(s) Thermal balloon endometrial ablation under patient-controlled sedation. Main outcome measure(s) Change in intrauterine pressure during the treatment cycle and risk factors associated with treatment failure. Result(s) A spontaneous decrease in intrauterine pressure occurred in most patients (93%). The mean (±SD) decrease was 34.1 ± 14.9 mm Hg, or 19.5% ± 9.1%. The treatment failed in 10 patients (13.9%), and the mean end pressure was significantly lower in this group (131.1 ± 14.1 mm Hg vs. 145.1 ± 18.0 mm Hg; P=.02). The chance of success of treatment was significantly lower when the end pressure was <140 mm Hg (odds ratio, 0.42 [95% CI, 0.27 to 0.68]; P=.01), the intrauterine volume was >10 mL (odds ratio, 0.43 [95% CI, 0.22 to 0.83]; P=.058) and the uterus was retroverted (odds ratio, 0.36 [95% CI, 0.20 to 0.65]; P=.008). Conclusion(s) Maintaining high intrauterine pressure during the treatment cycle and correction of the retroversion may help to improve treatment success in thermal balloon endometrial ablation.
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