Abstract
Aryl- N-tosylaziridines and epoxides smoothly undergo ring-opening with pyrrole and indoles in the presence of 5M lithium perchlorate in diethyl ether (LPDE) at ambient temperature to afford the corresponding 2- and 3-alkylated pyrroles and 3-alkylated indoles in high yields with high selectivity. LiOTf is also found to be an effective catalyst for this transformation.
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