Abstract
In vivo, cells can grow in 3D and significantly differ from cells grown in 2D. Imitating an extracellular microenvironment, 3D cell culture platforms using dynamic hydrogels have emerged, which can be altered by external stimuli, such as light, to mimic the chemical and physical properties of the native cellular environment. Photo-sensitive matrices enable the non-invasive, on-demand assembly of proteins and allow them to take influence on cells in real-time with high accuracy.
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