Abstract

First line anti-tubercular drugs are known to cause various adverse drug reactions including cutaneous reactions. We report a rare case of anti-tubercular treatment (ATT) induced lichenoid skin reaction in a 58 years old female with no prior history of rashes. She was put on fi xed dose combination (FDC) tablets of fi rst line anti-tuberculosis drugs and developed reaction one month after initiation of therapy.

Highlights

  • Lichenoid skin reactions are rare cutaneous manifestation to develop in the patients on antitubercular drug[1]

  • The spectrum of cutaneous adverse drug reaction associated with anti-tubercular treatment (ATT) include various syndromes like Stevens – Johnson syndrome, lichenoid skin reaction, DRESS syndrome, and drug hypersensitivity syndrome[2]

  • After a huge success in the outcomes, fixed dose combination (FDC) was introduced for all ATT drug regimen under Directly Observed Treatment Short-course (DOTS) in 2015

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Summary

CASE REPORT

Lichenoid Skin Reaction in a Patient on Anti-Tubercular Drugs: a Rare Case Report. First line anti-tubercular drugs are known to cause various adverse drug reactions including cutaneous reactions. We report a rare case of anti-tubercular treatment (ATT) induced lichenoid skin reaction in a 58 years old female with no prior history of rashes. She was put on fixed dose combination (FDC) tablets of first line anti-tuberculosis drugs and developed reaction one month after initiation of therapy.

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