Abstract

- The etiology of lichen planus is predominantly autoimmune, with various associations. A variable association of oral lichen planus with hepatitis- C infection has been reported extensively in the literature. The same association has not been studied in this geographical region. The present study was undertaken to evaluate the association of all clinical types of lichen planus with hepatitis-C virus infection in subjects hailing from this region. To evaluate the association of lichen planus with hepatitis-C infection. The study was conducted in a tertiary care hospital. This was an observational, case control study The study comprised of 100 cases and an equal number of age and sex matched healthy controls. The serum of both the groups was subjected to 4 generation HCV tridot test to detect anti HCV antibodies. The data was subjected to descriptive and inferential statistical analysis using mean, percentage, frequency and Chi square test. The seropositivity of HCV antibody could not be demonstrated in any of the cases or control subjects. The association of lichen planus with hepatitis C virus infection could not be demonstrated in our study.

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