Abstract
LHERMITTE'S sign (electric shock-like dysesthesia produced by neck flexion) was first described by Marie and Chatelin in 1917.<sup>1</sup>In 1924, Lhermitte et al described in detail a patient with multiple sclerosis and electric dysesthesias.<sup>2</sup>Since then, Lhermitte's sign has been described in association with tumors of the cervical cord, arachnoiditis, cervical spondylitis, radiation myelitis, subacute combined degeneration of the cord, and nitrous oxide exposure.<sup>3-5</sup>Recently, we have seen two patients with Lhermitte's sign who were found to have cobalamin (vitamin B<sub>12</sub>) deficiency. <h3>Report of Cases</h3><h3>Case 1.—</h3> A 38-year-old woman complained of fatigue and electric dysesthesia with neck flexion for several months prior to evaluation. Examination revealed a mild decrease in vibration and position sense in the extremities. Initial laboratory data included a hemoglobin level of 9.3 g/dL, a leukocyte count of 2.6×10<sup>9</sup>/L, and a platelet count of 330 ×10<sup>9</sup>/L. The blood
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