Abstract
Abstract Enhanced Recovery after Surgery (ERAS) protocols aim to improve perioperative care and patient outcomes. A pragmatic, multicenter, randomized controlled trial will be conducted in the Democratic Republic of Congo (DRC) to assess ERAS’ efficacy compared to the current standard of care (SOC) for glioma patients. Eligible providers will be randomized at the surgical team level to ERAS or SOC, ensuring consistent practices within teams. Hospitals representing diverse healthcare settings will be included, and randomization will be stratified by hospital to ensure balance. 100 glioma patients (50 in each group) will be included, and primary analysis expects fewer post-operative complications and shorter hospital stays in the ERAS group, with higher patient satisfaction. Subgroup analyses will be conducted by hospital center. Randomization and stratification aim to mitigate provider and hospital-specific influences, enhancing the study’s validity and equitable representation. This unique trial design seeks to provide insights into ERAS benefits for glioma patients in resource-constrained settings, guiding clinical practice and healthcare policy to improve care and outcomes.
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