Abstract
AbstractN‐Alkylation of aromatic amines with alcohols is an efficient route for the synthesis of higher benzylamines. Herein, we explore an efficient catalytic activity of tin(ii) triflate for the N‐alkylation of secondary anilines with alcohols for the synthesis of tertiary benzylamines. Mechanistic studies suggest that the developed protocol follows direct nucleophilic substitution pathway instead of imine or enamine pathway. The developed method is also useful for the synthesis of secondary amines as well as late stage functionalization of naturally occurring alcohols.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
