Abstract
Acute heart failure (AHF) is common among trauma patients with pre-existing coronary artery disease (CAD) and myocardial perfusion defect. The therapy is aimed at increased contractility while decreasing afterload and includes β1-adrenergic agents and phosphodiesterase III inhibitors, which act by increasing the intracellular calcium (Ca) concentration, thus markedly increasing myocardial energy consumption and risk of arrhythmias. The new Ca sensitizer levosimendan enhances cardiac performance without increasing myocardial energy demand and oxygen consumption. We report new use of levosimendan in polytrauma victims with AHF.
Highlights
Mortality was significantly higher for the thrombocytopenic patients (66.95% vs. 41.76%, P = 0.000), except for those who underwent specific therapy (37.5%, P = 0.000)
In this study we aimed to investigate the relationship between thyroid hormone abnormalities and major cardiovascular events and sudden cardiac death at 3 and 6 months after discharge in patients who were admitted to the Emergency Department with acute coronary syndrome
Cuthbertson HG, et al.: The PRaCTICaL study of nurse led, intensive care follow-up programmes for improving long term outcomes from critical illness: a pragmatic randomised controlled trial
Summary
The aim of this study was to assess and compare the ability of the automatically and continuously measured pulse pressure variation (PPV) obtained by an IntelliVue MP monitor and stroke volume variation (SVV) measured by FloTracTM/VigileoTM to predict fluid responsiveness in septic shock patients. Neutrophil gelatinase-associated lipocalin (NGAL) is a novel renal biomarker showing promising results in prediction of AKI in patients across different clinical settings Another potential marker is the resistive index (RI) of renal interlobar artery (calculated as (peak systolic velocity – end diastolic velocity) / peak systolic velocity), which has been shown to be useful in identifying those who will develop AKI in patients with septic shock. Binks R: Prevalence, clinical management and risks associated with acute faecal incontinence in the critical care setting: the FIRST questionnaire survey. Critical Care 2011, 15(Suppl 1):P480
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