Abstract

Background: Central post-stroke pain (CPSP) is a severe and distressing pain condition. Treatment of CPSP is based on amitriptyline and anti-epileptic drugs (AED) but limited by side effects and unsatisfying efficacy. Levetiracetam (LEV) is a novel AED with a favourable adverse event and safety profile. Experimental neuropathic animal and human pain models show an analgesic effect of LEV.

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