Abstract

Abstract 45 Background: The National Cancer Institute Cancer Centers Program is one of the anchors of the US cancer research effort. The National Cancer Institute’s Center for Global Health (CGH) has supported several initiatives that leverage this national resource to advance cancer research and related activities in low- and middle-income countries (LMICs). In 2013, CGH awarded 1-year contracts to 15 cancer centers and partner institutions in LMICs to advance cancer research capacity in LMICs through research, training, and capacity building in a range of areas, including informatics, data sharing, and biorepositories. In 2015, CGH awarded 2-year administrative grant supplements to 10 cancer centers and partner institutions in LMICs to support cancer prevention and control research. Domains included clinical and translational research, detection and diagnosis, surveillance and registries, knowledge sharing, implementation science, informatics and mHealth, and malignancies associated with HIV and chronic infection. The aim of this work was to assess the outcomes and impacts of these investments, including scientific progress, capacity development for cancer research and related activities in LMICs, and capacity development for future partnerships among cancer centers and LMIC institutions, as well as to reflect on how initiative characteristics, such as scope and mechanism, influence outcomes and impacts. Methods: We performed qualitative content analysis of progress reports and final reports. Results: Findings highlight the outcomes and impacts of these investments in partnerships among cancer centers and LMIC institutions, and shed light on the influence of funding initiative characteristics. Conclusion: Findings reflect the value of these investments to advance cancer research and related activities in LMICs, and help to inform future CGH engagement with cancer centers. AUTHORS' DISCLOSURES OF POTENTIAL CONFLICTS OF INTEREST No COIs from the authors.

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