Abstract

Antibiotics are among the most commonly prescribed medications, and there is evidence to guide the optimal use of these agents for most situations encountered in clinical medicine, including for both treatment and prophylaxis. Nevertheless, clinicians routinely prescribe antibiotics in ways that diverge from this evidence, such as prescribing them when not indicated, for durations longer than necessary, or selecting broad-spectrum antibiotics when a narrower-spectrum agent would suffice.1,2 This overuse of antibiotics contributes to the public health crisis of antibiotic resistance while exposing patients to potential antibiotic-related harms.

Highlights

  • The implementation process may vary based on the healthcare setting, the antibiotic prescribing practice that needs to be improved, and the stakeholders involved. Even though those who participate in antibiotic stewardship know this to be true from experience, a gap exists in our understanding of the way each of these factors can be addressed to increase the likelihood of implementation success.[4]

  • We argue that what has been historically defined as antibiotic stewardship strategies, such as prospective audit and feedback and prior authorization, can be described as implementation strategies

  • Identifying the evidence–practice gap Implementation science is the systematic study of methods to promote the uptake of proven approaches to improve health outcomes; implementation research projects must clearly identify the evidence-based clinical treatment, practice, organizational, or management intervention that is the focus of the implementation effort

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Summary

SHEA White Paper

Leveraging implementation science to advance antibiotic stewardship practice and research Daniel J. The implementation process may vary based on the healthcare setting, the antibiotic prescribing practice that needs to be improved, and the stakeholders involved Even though those who participate in antibiotic stewardship know this to be true from experience, a gap exists in our understanding of the way each of these factors can be addressed to increase the likelihood of implementation success.[4]. In this white paper, we discuss how to apply key implementation science principles and methods to studies of antibiotic stewardship. Identifying the evidence–practice gap Implementation science is the systematic study of methods to promote the uptake of proven approaches to improve health outcomes; implementation research projects must clearly identify the evidence-based clinical treatment, practice, organizational, or management intervention that is the focus of the implementation effort.

Toyota lean Six sigma
Implementation strategies defined
Utilize financial strategies
Choosing an implementation science framework
Establishing stakeholder engagement
Choosing an implementation strategy or a bundle of strategies
Evaluating the implementation process
Putting it all together
Preimplementation Implementation Sustainment
Implementation Sustainment
Adherence to the original protocol or the intended intervention
Integration of a practice within a setting

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