Leveraging a New ICD-10 Diagnosis Code to Characterize Hospitalized Patients With Primary Sclerosing Cholangitis

Abstract

Primary sclerosing cholangitis (PSC) is a progressive cholestatic liver disease characterized by inflammation and destruction of the biliary tree, often leading to cirrhosis requiring liver transplantation.1,2 PSC is rare, affecting ∼1–16 per 100,000 in the United States,1 and is typically considered a disease of young White males.1,3 However, with changing demographics of US population in terms of age, gender, and race/ethnicity, it is unknown whether demographics of patients with PSC has also shifted.