Abstract
Serum levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) of Macaca mulatta females were compared by radioimmunoassay after iv and intrapituitary administration of sheep (o) and rabbit (ra) median eminence extracts (SME) and synthetic LH-releasing hormone (LH-RH). Both intrapituitary infusion and iv injection of oSME and raSME caused nearly equal and significant (p < 0.05) elevations in serum levels of LH within 30 min. Intrapituitary infusion of 40 μg of LH-RH into rhesus at each of 3 stages–days 6 to 7, 11 to 14, or 20 to 23–of their menstrual cycles also caused significant, but equal, increases in serum LH. In contrast, an iv injection of 40 or 85 ng LH-RH during the early follicular or periovulatory stages of the cycle failed to elevate serum LH or FSH significantly above preinjection levels. Since the concentrations of serum LH after LH-RH never approached the LH levels observed during the spontaneous midcycle surge regardless of the LHRH dosage, its mode of administration, or t...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
