Levels of interleukin 1-beta and soluble urokinase plasminogen activation factor in peri-implant sulcular fluid of cement- and screw-retained dental implants.

Abstract

The present study compares interleukin 1-beta (IL-1β) and soluble urokinase plasminogen activation factor receptor (suPAR) levels in periimplant sulcular fluid (PISF) of patients with cement-retained (CR) and screw-retained (SR) implants. Patients with CR and SR implants were encompassed. Demographic data was collected and implant-related characteristics (geometry, insertion torque, loading and retention protocol, jaw location, duration in function and depth of insertion) were retrieved from records. Modified plaque index (mPI), crestal bone loss (CBL) probing depth (PD) and modified bleeding index (mBI) were measured. suPAR and IL-1β levels were assessed in PISF. Statistical comparisons were done and correlation between clinicoradiographic parameters and PISF IL-1β and suPAR were assessed. P<0.05 were judged statistically significant. Clinical and radiographic parameters showed no difference among SR and CR implants. There was no difference PISF volume among patients with CR (0.22±0.004 μl) and screw-retained (0.19±0.005 μl) implants. Levels of IL-1β and suPAR in patients with CR and SR implants were 50.08±0.6 ng/ml and 44.6±0.08 ng/ml, and 0.28±0.05 ng/ml and 0.22±0.006 ng/ml, respectively. Implants with CR or SR restorations are comparable to one another in terms of clinico-radiographic status and demonstrate IL-1β and suPAR levels within the normal range in the PISF provided oral hygiene is stringently maintained.