Abstract

Introduction of the ketogenic diet did not change the plasma levels of antiepileptic drugs in an open study of 51 children (mean age 6.6 years) with refractory epilepsy studied at Karolinska University Hospital, Stockholm, Sweden.

Highlights

  • Introduction of the ketogenic diet did not change the plasma levels of antiepileptic drugs in an open study of 51 children with refractory epilepsy studied at Karolinska University Hospital, Stockholm, Sweden

  • Hot water epilepsy is a benign form of reflex epilepsy, typically complex partial with temporal lobe localization, and occurring most frequently in children and young adults, males predominantly

  • Clinical features were similar to those reported in the Turkish clinic patients: ages ranged from 8 months to 58 years, 28% below 6 years; males predominated 2.65:1; only 7% had a history of febrile seizures; 67% had HW-induced complex partial seizures; and 30% had spontaneous non-reflex epilepsy

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Summary

Introduction

Introduction of the ketogenic diet did not change the plasma levels of antiepileptic drugs in an open study of 51 children (mean age 6.6 years) with refractory epilepsy studied at Karolinska University Hospital, Stockholm, Sweden. Hot water epilepsy is a benign form of reflex epilepsy, typically complex partial with temporal lobe localization, and occurring most frequently in children and young adults, males predominantly. Reports of HWE are most prevalent in India and Turkey, where sitting to bathe and pouring hot water over the head from a bowl are common customs.

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